We develop and apply integrated, multidisciplinary approaches to advance:
- Safety and efficacy assessment
- Mechanistic understanding of material–biological interactions
- Regulatory science and risk evaluation
Our work combines advanced experimental models with computational approaches to generate robust, reproducible, and mechanistically informed data that supports translational research and evidence-based decision-making.
Our activities are focused on advancing the field through:
- Integration of existing knowledge to address critical gaps in nanomedicine and nanotoxicology
- Development and validation of scientifically grounded, regulatory-relevant methodologies supporting Safe-and-Sustainable-by-Design (SSbD) nano-enabled products
- Application, optimisation, and standardisation of advanced analytical, biological, and computational approaches, including:
- Mechanism-driven testing strategies
- New Approach Methodologies (NAMs)
- High-throughput and high-content analyses
- Establishment of robust methodological frameworks for nanomaterial risk assessment with relevance for regulatory science and long-term implementation