Members of the research team led by Dr. Ivana Vinković Vrček, in collaboration with international partners, have published a new paper on the potential endocrine effects of nanoplastics in the journal Particle and Fibre Toxicology, titled “Surface-driven endocrine activity of nanoplastics: polymer- and size-dependent estrogen and androgen receptors modulation without steroidogenesis perturbation”.
The study shows that the effects of nanoplastic particles on estrogen and androgen receptors depend on the type of polymer, particle size, and their mixtures, opening new questions for the risk and safety assessment of nanoplastics exposure.
The results of this study shift the assessment of the endocrine effects of nanoplastics beyond the previously often-used polystyrene models and provide an important foundation for future exposure monitoring and risk assessment in real environmental conditions and consumer exposure.
The paper was supported by European and national projects, including PARC, PlasticsFate, as well as the infrastructure and development support of the Institute.
Link to the paper: https://link.springer.com/article/10.1186/s12989-026-00692-7
